Graham remained optimistic that McCain would eventually support the bill, telling an ABC affiliate on Thursday, "He won't vote because of our friendship, I would never ask him".
If it were to pass the Senate, the bill would head to the U.S. House, which passed a different Obamacare repeal bill in May.
Collins, who just two days ago said she was "leaning against" the legislation, on Sunday declared in an interview on CNN's "State of the Union": "It is very hard for me to envision a scenario where I would end up voting for this bill".
Collins' all but certain opposition leaves the White House and party leaders desperate to rescue their promise to repeal Obama's Affordable Care Act with one immediate option: trying to change the mind of at least one opponent. Collins said sponsors were making last-minute adjustments in the measure's formulas used to distribute federal money to the states, and the measure's sponsors said they still meant to plow ahead. Aides to Senate Majority Leader Mitch McConnell said earlier this week that he planned to force a vote, and that could still happen, to clearly show who was for the plan, and who was not. But Maine GOP Sen.
The plan would create a framework through which the 50 states would get block grants to design health coverage initiatives for people now covered on Obamacare exchanges and under the law's Medicaid expansion. "But I'm just not for this block granting concept because it is affirmative vote that I have agreed to keep Obamacare". Trump said, adding that the health bill was "great for Arizona". Judy Woodruff talks to Sen. "I would consider supporting legislation similar to that offered by my friends Senators Graham and Cassidy were it the product of extensive hearings, debate and amendment".
Gov. Paul LePage joined Vice President Mike Pence in Washington Friday.
Speaking to CBS News' John Dickerson, Collins said she'll remain uneasy until the Congressional Budget Office releases its latest projection for the bill's impact. Bill Cassidy, R-La., and Lindsey Graham, R-S.C., would affect Medicaid, costs and people with pre-existing medical conditions.
Republicans have been desperate to make one last push to repeal Obamacare, but so far signs point to a reality where the party may not be successful once again. So not only would people lose access to health care that they need, it would be a devastating blow to the community.
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Collins' vote is key. Lisa Murkowski, another Republican who has yet to announce where she stands on Graham-Cassidy.
Senate Republicans have seen their previous attempts at Obamacare repeal fall short by a small number of votes. John McCain, said he opposes the bill.
The renewed GOP drive has encountered widespread opposition from health industry groups, which have strongly opposed the effort.
That change would cut federal funding for Medicaid compared to the course set under current law.
While President Donald Trump tweeted Saturday that Paul "may find a way to get there for the good of the party", there is limited optimism on that front on Capitol Hill. Tell that to the people of Arizona who were deceived. States could loosen coverage requirements under the law's mandates, including prohibiting insurers from charging seriously ill people higher premiums and letting them sell policies covering fewer services.
Democrats are as rare in Alabama as Louisiana State fans, but Trump warned that Moore, a controversial religious fundamentalist, would have "a very good chance of not winning in the general election" later this year.
Collins spoke about the bill during an appearance in her home state of Maine.