Manfred said Major League Baseball is surveying all 30 teams to see how they handle such situations "as a prelude to giving consideration to some more industry wide guidelines in this area".
Barnes' 90-mph pitch was more unsafe, targeted too close to Machado's head.
Machado went on an expletive-laden rant after the Red Sox's 5-2 win Tuesday, blasting Sale and the team and saying he "lost respect for that organization, that coaching staff and everyone over there".
The Red Sox held a 3-1 lead going into the fourth inning before Baltimore's offense exploded for five runs to take control of the game.
Kellyanne Conway calls Anderson Cooper's epic eye roll sexist
Conway last month attempted to redefine feminism - and the dictionary really wasn't impressed. "Let me tell you something". I said, "thanks for the trip down memory lane" and talked about winning MI and then he rolled his eyes.
'Wages won't keep up:' UK central bank says inflation biting
Brexit has exacerbated a trend of weak or non-existent pay growth that started well before last year's referendum. The BoE will be deciding on interest rates and quantitative easing, as well as publishing its inflation report .
Bill Shorten issues stinging budget reply
Finance Minister Mathias Cormann called on Shorten to submit his speech to the Parliamentary Budget Office for costing. It would mean a worker on $55,000 would pay $275 extra a year, while someone on $80,000 would face an extra $400.
And now, after this week, Machado has something else in common with Alex Rodriguez: He's the chief villain in a rivalry with the Boston Red Sox. Whether Manfred's warning will prevent further retaliation remains to be seen, but given the league's leniency so far, it may not be enough.
Fast forward to this week. "It's f--ing bulls--." Machado said. Go ahead and watch it again online.
"What nonsense?" Orioles third baseman Manny Machado said tongue-in-cheek after being at the center of the drama - and hitting a monster three-run homer in the series finale. "It's been a month now that I've struggled a little bit, but I'm finally, little by little, taking baby steps, feeling better at the plate, seeing the ball a little better, still making good contact with the ball". "For him to get away with it, and I hit a guy with a curveball and they throw me out of the game, that's pretty ridiculous". The Sox are now 15-13 after splitting their last 4-game series with the Orioles, who are now 1st place in the AL East.
Red Sox: Farrell said knuckleballer Steven Wright, who was put on the disabled list Monday with a sprained left knee, is "contemplating the options that are available to him and "surgery's not ruled out.".