Runaway leaders Bayern Munich suffered only their second Bundesliga defeat of the season when they were beaten 1-0 at surprise package Hoffenheim on Tuesday.
While the result seems unlikely to stop their inexorable march towards a record fifth successive title, it is hardly ideal so early in a massive month that includes two meetings with Borussia Dortmund, as well as a Champions League quarter-final tie against Real Madrid.
While Muller is ruled out against Hoffenheim, Bayern will be able to recall Spanish duo Javi Martinez and Xabi Alonso to the side after they served their suspensions. Our first half wasn't so good.
Chances were plentiful for Bayern Munich, but it was Andrej Kramaric who helped secure a dramatic win for Hoffenheim.
Despite a plethora of attacking options on his bench, Bayern coach Ancelotti kept faith with the starting XI at the start of the second half.
Dortmund gained momentum in the closing period and rounded off the game with a third goal when Aubameyang utilized Kagawa's through ball to round Hamburg goalie Rene Adler for the 25th goal of the season.
Despite being on the back foot, Aubameyang missed another great chance when he struck Adler in the face.
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Dortmund then wrapped up the victory with two goals in the last 10 minutes.
With the victory, Dortmund remain on fourth place, one point adrift of third.
Hamburg are only just clear of the relegation places, but are unbeaten in their last four league games after Lewis Holtby scored their 92nd-minute victor in Saturday's 2-1 victory against Cologne.
Kramaric scored the only goal of the encounter, as Hoffenheim dominated proceedings for most of the first half and deserved to get a second goal.
"It was hard in the second half, but we got ourselves in front of every shot".
Merkel was there to see the home side wearing jerseys highlighting an initiative supported by around 180 companies to promote the integration of refugees into the workplace.