And within five minutes of going two-nil up, Barca had their third and this time Messi went for power, rather than finesse but found the same devastating result. They used their high-pressing well to cut off passing lanes for their opponents.
Down the other end, Marc-Andre ter Stegen was forced into his only meaningful contribution, as he stood tall to block a close-range effort from Steven N'Zonzi.
The Catalans were in the oppositions' 18-yard-box nearly at will. His league total of 24 goals this season is three less than scoring leader Messi, who got his first of the night in the 28th minute with an easy shot from inside the area after a combination of passes between Neymar and Suarez.
25' GOAL What a fantastic finish from Suarez!
Suarez got in on the act. His first strike was a case of that, tapping home from Suarez's cross, and his second goal was an impressive volley from inside the area.
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The Colombia global slotted the opener after good work from Marco Asensio and, though Leganes hit two goals to give them a fright, Madrid held on for the win. That will be tricky to deal with, but at least they're better off than Sevilla, who will be without a key defensive trio with both Gabriel Mercado and Adil Rami hurt, plus Sergio Ecudero suspended. Barcelona took their foot off the pedal, knowing their strong first half wrapped up three vital points.
The last act of the game summed up Sevilla's frustrations as Vitolo received a second yellow card for a petulant kick out at Neymar as Barca saw out a comfortable success.
Sanchez has continued to shine during his time in the Premier League, and says that witnessing the way Messi mentally approaches the game has had a big influence on his career. They lost against Deportivo in March.
Alvaro Morata scored twice as Real Madrid maintained a two-point lead over Barcelona at the top of La Liga by making light of Cristiano Ronaldo and Gareth Bale's absence in a 4-2 win at Leganes. They face an away trip to Malaga on Saturday, while Los Blancos at home against fierce rivals Atletico in what should be a cracking game.
NAIJ.com recalls that Enrique has been coach for Barcelona since 2014 and he has led them to two La Liga titles, two Copa del Rey, one UEFA Champions League title, One UEFA Super Cup and One FIFA Club World Cup. It all sounds so fitting.