The drawn first Test in Dunedin was played on a slow, turning pitch and New Zealand picked two spinners, who bowled a combined 106 overs out of a total of 224.4 during South Africa's two innings.
New Zealand, heading into the Test, have a few glaring issues on hand, the most significant of which is the injury concern to Trent Boult.
Left-arm spinner Mitchell Santner opened the bowling for New Zealand in both games‚ and in one of them he and off-spinner Jeetan Patel became the first pair of slow bowlers to take the new ball in ODI history.
New Zealand: Tom Latham, Jeet Raval, Kane Williamson (capt), Neil Broom, Henry Nicholls, James Neesham, BJ Watling, Colin de Grandhomme, Tim Southee, Neil Wagner, Jeetan Patel.
It will be Broom's Test debut but he has played 30 one-day internationals including three in the recent series against South Africa where he had scores of two, two and a duck.
The 33-year-old right-hander has been called in as cover for injured 81-Test veteran Ross Taylor, and du Plessis is expecting his bowlers to target the Test rookie.
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Senior bowler Tim Southee confirmed he would return for Thursday's test in Wellington, in place of Boult, after being dropped for the Dunedin draw.
"I said before the series, if you can get rid of Williamson and Taylor, there's a lot of pressure on the rest of the batting line-up", du Plessis said.
"We couldn't get rid of Kane in the first test and they were successful as a unit".
The Proteas have played six Tests at the Basin, winning four and drawing two.
"So there lies the secret". He's a guy who's not scared of a challenge.